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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP21
All Species:
13.03
Human Site:
Y497
Identified Species:
47.78
UniProt:
Q5T5U3
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T5U3
NP_065875.3
1957
217331
Y497
H
R
T
R
S
W
D
Y
I
E
G
Q
D
E
T
Chimpanzee
Pan troglodytes
XP_507699
1957
217438
Y497
H
R
T
R
S
W
D
Y
I
E
G
Q
D
E
T
Rhesus Macaque
Macaca mulatta
XP_001100413
1957
217419
Y497
H
R
T
R
S
W
D
Y
I
E
G
Q
D
E
T
Dog
Lupus familis
XP_548158
1061
116725
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFV3
1944
215724
Y492
H
R
T
R
S
W
D
Y
I
E
G
Q
T
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506140
1948
216249
D495
N
H
R
T
R
S
W
D
Y
L
G
G
Q
G
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DFG0
1926
214694
H491
R
S
E
S
W
D
Y
H
A
R
K
G
D
F
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
27.3
N.A.
86
N.A.
N.A.
77
N.A.
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
99
35.6
N.A.
90.5
N.A.
N.A.
84.8
N.A.
74.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
86.6
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
58
15
0
0
0
0
58
0
29
% D
% Glu:
0
0
15
0
0
0
0
0
0
58
0
0
0
58
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
72
29
0
15
0
% G
% His:
58
15
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
58
15
0
0
% Q
% Arg:
15
58
15
58
15
0
0
0
0
15
0
0
0
0
0
% R
% Ser:
0
15
0
15
58
15
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
58
15
0
0
0
0
0
0
0
0
15
0
43
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
15
58
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
58
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _